NEXTRIAZ-O Injection
Ceftriaxone-1000 mg
Indication
*LRTI
*Perioperative prophylaxis
*UTI
*Septicemia
*Meningitis
*Intra-abdominal infections
*URTI
Ceftriaxone:
A parental 3rd generation cephalosporin with a potent bactericidal activity.
Effective against wide range of gram+ve and gram-ve bacteria.
Highly stable to most beta-lactamases and exhibits minimal immunosuppressant activity.
More stable as compared to other 3rd generation cephalosporin.
Exhibits its bactericidal effect by inhibiting the bacterial cell wall synthesis.
Drug of choice in typhoid fever.
Excellent in treating complicated UTI.
Single I.M dose significantly better than 10-day oral amoxicillin in AOM.
High cure rate & reduced treatment cost in LRTI.
Superiority in bacterial meningitis.
Convenient O.D dose n adults & BD dose in children.
Excellent Therapeutic index (CEFTRIAXONE 92%) results in greater therapeutic tissue concentration.